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I started
this website for several reasons ... (1) to make certain running information readily
available to section III fans and (2) to provide
a ranking and analysis of running performances that is not available
anywhere else.
I'm a 1968 graduate of Tully High. During the
1970's, I sent a fair amount of time training for the decathlon ...
overall, I was barely mediocre with top scores in the lower to mid
6000s. However, I was able to meet many great track people and learn
from them. I learned a great deal about weight lifting (and how it
helps in track) from Liverpool-Baldwinsville-Marcellus Coach Oscar Jensen. In contrast to most high school coaches, I'm not
a school teacher ... I'm an environmental scientist with degrees
from Clarkson University ... I've outlined my professional career
below.
I work for Syracuse Research Corporation
(Environmental Science Center) as an environmental scientist. Our
main corporate website is available at www.syrres.com
... I developed portions of the Environmental website section (Estimation
Software and sections of the Databases).
Primary funding for the Environmental
Science Center comes from U.S. Environmental Protection Agency (EPA) and
other regulatory agencies. Funding from private industries (chemical
and pharmaceutical firms) has been increasing. My major
responsibility is development of methodology and computer software to
predict physical and chemical properties of organic compounds for
assessment of environmental fate and transport. The software I've
developed is used by the U.S. EPA (evaluation of Toxic Substances Control
Act and pre-manufacture
chemicals), German EPA, Danish EPA, and other governmental regulatory
agencies around the world. Before selling the copyright to the US
Environmental Protection Agency, software sales has occurred in more than 30 countries. Pharmaceutical firms use the software for high-throughput
screening and combinatorial chemistry during the drug design evaluation. I
maintain large chemical property databases that I use for data analysis
and pattern recognition ... I've made several databases available for free
use to scientists around the world via the Internet ... The software can
be downloaded for free from the US EPA at:
http://www.epa.gov/oppt/exposure/pubs/episuite.htm
I'm the primary author of various
scientific journal articles describing chemical structure estimation
methodologies. Articles have been published in peer-reviewed journals such
as the Journal of Pharmaceutical Sciences, Environmental Science &
Technology, Environmental Toxicology & Chemistry, and Chemosphere.
I'm the co-author of two books ["Handbook of Environmental
Degradation Rates" (Lewis Publishers) and "Handbook of Physical
Properties of Organic Compounds (CRC Press)] and contributing author to
about half a dozen other books. I also peer-review several manuscript
submissions for various journals each year. I have written the
Environmental section for about 300 chemicals in the National Library of
Medicine's Hazardous Substances Databank (HSDB).
Selected Publications:
Meylan W; Boethling R; Aronson D; et al. (2007) Chemical
structure-based predictive model for anaerobic biodegradation potential.
Environ Toxicol Chem 26(9):1785-1792.
Howard P; Meylan W; Aronson
D; et al. (2005) A new biodegradation prediction model specific to
petroleum hydrocarbons. Environ Toxicol Chem 24(8):1847-1860.
Meylan WM; Howard PH. (2005) Estimating octanol–air partition coefficients
with octanol–water partition coefficients and Henry's law constants.
Chemosphere 61:640-644.
Aronson D; Meylan W; Howard P; et al.
(2005) The calibration of environmental biodegradation half-lives for use
in waste water treatment plants. Conservation of Clean Air and Water in
Europe. SRC TR-05-030.
Stewart S; Aronson D; Meylan W; et al.
(2005) Critical evaluation of BCF hydrocarbon database and recalibrate of
BCFWIN specifically for petroleum hydrocarbons. Conservation of Clean Air
and Water in Europe. SRC TR-05-031.
Boethling RS; Howard PH; Meylan
WM. (2004) Finding and estimating chemical property data for environmental
assessment. Environ Toxicol Chem 23:2290-2308.
Meylan WM; Howard
PH. (2003) A review of quantitative structure-activity relationship
methods for the prediction of atmospheric oxidation of organic chemicals.
Environ Toxicol Chem 22(8):1724-1732.
Rosenberg SA; Hueber HE;
Aronson D; Meylan, W; et al. (2003) Syracuse Research Corporation's
chemical information databases: Extraction and compilation of data related
to environmental fate and exposure. Sci Technol Libr 23(4):73-87.
Chappell L; Meylan W; Howard P. (2003) Grouping organometallic substances
on the domestic substance list (DSL) and verifying simple molecular input
line entry system (SMILES) notations. Environment Canada. SRC TR-03-116b.
Howard P; Meylan W. (2001) Toxic chemicals: assessing environmental
fate and exposure. Chem Eng (N Y )108(3):91-96.
Meylan WM; Howard
PH. (2000) Estimating log P with atom/fragments and water solubility with
log P. 19:67-84.
Griffin S; Goodrum PE; Diamond GL; et al. (1999)
Application of a probabilistic risk assessment methodology to a lead
smelter site. Hum Ecol Risk Assess 5(4):845-868.
Meylan WM; Howard
PH; Boethling RS; et al. (1999) Improved method for estimating
bioconcentration/bioaccumulation factor from octanol/water partition
coefficient. Environ Toxicol Chem 18(4):664-672.
Goodrum P;
Diamond G; Meylan W. (1999) User's guide for the integrated stochastic
exposure (ISE) model for lead. MS-Windows version 1.40. Integrated
Solutions & Services, Inc. SRC TR 99-004.
Goodrum P; Diamond G;
Meylan W. (1998) Summary of beta testing comments and recommendations for
further development of the integrated stochastic exposure (ISE) model for
lead. Integrated Solutions & Services, Inc. SRC TR-98-014.
Howard
PH; Meylan WM, eds.(1997) Handbook of physical properties of organic
chemicals. Boca Raton, FL: Lewis Publishers. 3, 12, 49, 226, 518, 723,
Howard PH; Meylan WM. (1997) In: Howard PH, Meylan WM, Funk J, et al,
eds. Handbook of physical properties of organic chemicals. New York, NY:
Lewis Publishers.
Howard PH; Meylan WM. (1997) Prediction of
physical properties, transport, and degradation for environmental fate and
exposure assessment. In: Chen F, Schuurmann G, eds. Quantitative
structure-activity relationships in environmental sciences. Pensacola:
SETAC Press. 185-205.
Meylan W; Howard P; Aronson D; et al. (1997)
Improved method for estimating bioconcentration factor (BCF) from octanol-water
partition coefficient. Office of Prevention, Pesticides and Toxic
Substances, U.S. Environmental Protection Agency. SRC TR-97-006.
Meylan W; Howard P. (1997) Improvement of the SRC atmospheric oxidation
program (AOP). Fraunhofer Institut fur Umweltchemie und Okotoxikologie.
SRC TR-97-008.
Meylan WM; Howard PH; Boethling RS. (1996) Improved
method for estimating water solubility from octanol/water partition
coefficient. Environ Toxicol Chem 15(2):100-106.
Durkin PR; Rubin
L; Withey J; et al. (1995) Methods of assessing dermal absorption with
emphasis on uptake from contaminated vegetation. Toxicol Ind Health
11(1):63-79.
Meylan WM; Howard PH. (1995) Atom/fragment
contribution method for estimating octanol-water partition coefficients. J
Pharm Sci 84(1):83-92.
Durkin P; Fanfarillo; Campbell; et al.
(1995) Final environmental impact statement, volume III of V, human health
risk assessment for the national gypsy moth management program. U.S.
Department of Agriculture. SRC TR-95-023.
Meylan W; Howard P.
(1995) Improvement of the SRC atmospheric oxidation program (AOP).
Fraunhofer Institut fur Umweltchemie und Okotoxikologie. SRC TR-95-008.
Meylan W; Howard P. (1994) Upgrade of PCGEMS water solubility
estimation method. Office of Pollution Prevention and Toxics, U.S.
Environmental Protection Agency. SRC TR-94-009.
Meylan W; Stiteler
W. (1994) Users's guide for the SMUSHT program. Environmental Criteria and
Assessment Office, U.S. Environmental Protection Agency. SRC TR-94-020.
Meylan W; Howard P. (1994) Validation of water solubility estimation
methods using Log Kow for Application in PCGEMS & EPI. SRC TR-94-024.
Boethling RS; Howard PH; Meylan W; et al. (1994) Group contribution
method for predicting probability and rate of aerobic biodegradation.
Environ Sci Technol 28:459-465.
Howard PH; Michalenko EM; Basu DK;
et al. (1993) In: Howard, PH, eds.Handbook of environmental fate and
exposure data for organic chemicals. 4. Solvents 2Chelsea, MI: Lewis
Publishers. 578.
Meylan WM; Howard PH. (1993) Computer estimation
of the atmospheric gas-phase reaction rate of organic compounds with
hydroxyl radicals and ozone. Chemosphere 26(12):2293-2299.
Beauman
J; Hueber AE; Sage G; et al. (1993) Environmental fate assessments of
chemical agents: TSCA CBI. U.S. Environmental Protection Agency. SRC
TR-93-021b.
Beauman J; Sage G; Meylan W; et al. (1993)
Environmental fate assessments of treaty verification chemicals. U.S.
Army, Armament Munitions and Chemical Command, Chemical Research and
Development Center. SRC TR-93-021a.
Meylan W; Howard P. (1993)
Programmer's guide for the estimation programs interface EPI. U.S.
Environmental Protection Agency. SRC TR-93-033.
Howard PH;
Boethling RS; Stiteler WM; et al. (1992) Predictive model for aerobic
biodegradability developed from a file of evaluated biodegradation data.
Environ Toxicol Chem 11:593-603.
Meylan W; Howard PH; Boethling
RS. (1992) Molecular topology/fragment contribution method for predicting
soil sorption coefficients. Environ Sci Technol 26(8):1560-1567.
Rubin L; Durkin P; Meylan W; et al. (1992) An analysis and validation of
methods for assessing dermal uptake of pesticides from contaminated
surfaces. Toxicologist 13(1):281.
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